Antipruritic Placebo Effects by Conditioning H1-antihistamine
نویسندگان
چکیده
منابع مشابه
Central effects of the H1-antihistamine, cetirizine.
BACKGROUND Effects of the H1-antihistamine, cetirizine, were studied on daytime alertness and performance to establish whether the drug would be suitable for use by air personnel and others involved in skilled activity. METHODS The investigation was carried out in six healthy volunteers, and the effects of the drug (5, 10, and 15 mg) were studied on sleep latency, subjective sleepiness, digit...
متن کاملH1-antihistamine treatment in young atopic children: effect on urticaria.
BACKGROUND There are few published, randomized, double-masked, placebo-controlled, clinical trials of interventions for urticaria in the pediatric population. OBJECTIVE To study the effect of long-term treatment with the H1-antihistamine levocetirizine on urticaria in young atopic children. METHODS In the randomized, double-masked, parallel-group Early Prevention of Asthma in Atopic Childre...
متن کاملEffects of H1 antihistamine therapy on the cytokine profile in chronic urticaria
Introduction Chronic urticaria (CU) is defined by the presence of recurrent urticarial lesions, transient, pruritic and erythematous, for a period of at least 6 weeks. The diagnosis of urticaria integrates a heterogeneous group of diseases emerging as a result of a great variety of causes (Zuberbier et al 2009). All types and subtypes share a distinctive pattern of skin reactions manifested by ...
متن کاملAntipruritic Effects of Botulinum Neurotoxins.
This review explores current evidence to demonstrate that botulinum neurotoxins (BoNTs) exert antipruritic effects. Both experimental and clinical conditions in which botulinum neurotoxins have been applied for pruritus relief will be presented and significant findings will be highlighted. Potential mechanisms underlying antipruritic effects will also be discussed and ongoing challenges and unm...
متن کاملInhaled clemastine, an H1 antihistamine inhibits airway narrowing caused by aerosols of non-isotonic saline.
Asthmatic subjects were challenged with aerosols of hyper- and hypotonic saline 15 min (Group A) and 90 min (Group B) after inhaling clemastine. Measurements were made of forced expiratory volume in one second (FEV1) before and after medication and after challenge. When the FEV1 values (% predicted) were compared on the active and placebo days they were higher 15 min after clemastine (p less th...
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ژورنال
عنوان ژورنال: Psychosomatic Medicine
سال: 2019
ISSN: 1534-7796,0033-3174
DOI: 10.1097/psy.0000000000000743